Thermo Fisher Scientific Phospho-MEK1/MEK2 (Ser217, Ser221) Polyclonal Antibody
인간, 마우스, 랫트에 반응하는 MEK1/MEK2 인산화 특이 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. 0.82 mg/mL 농도의 액상 제품이며, PBS/glycerol 버퍼에 보존됩니다. 세포 성장 및 분화 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:7,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S217 & S221 of human MAP2K1/MAP2K2 (MAP2K1 NP_0027461) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.82 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901814 |
Product Specific Information
- Positive Samples: HeLa, NIH/3T3
- Immunogen sequence: SMANS
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is a key component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003).
In brain tissue, this pathway plays an essential role in synaptic signaling (Adams and Sweatt, 2002).
Activated MEK1 functions as a dual-specificity kinase, phosphorylating both threonine and tyrosine residues on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-117184_MEK12_Q02750-1_Rabbit.svg, PA5-117184_MEK12_Q02750-1_Rabbit_PDP.jpeg, PA5-117184_MEK12_P36507-1_Rabbit.svg, PA5-117184_MEK12_P36507-1_Rabbit_PDP.jpeg)
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