Thermo Fisher Scientific PARN Monoclonal Antibody (UMAB143), UltraMAB
PARN 단백질을 인식하는 UMAB143 클론 단일클론 항체로, Western blot, IHC(P), ChIP 등 다양한 응용에 사용 가능. Human에 반응하며, 비결합형 동결건조 포맷으로 제공. 재구성 및 결합 실험 시 탈염 권장. 연구용으로만 사용.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| ChIP assay (ChIP) | Assay-Dependent |
| Peptide Array (Array) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB143 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)
Target Information
The protein encoded by this gene is a 3′-exoribonuclease belonging to the RNase D family. It preferentially degrades poly(A) tails of mRNAs, initiating mRNA decay in eukaryotic cells.
This protein also participates in silencing of maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated mRNA decay (NMD) of transcripts with premature stop codons.
Alternative splicing results in multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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