Thermo Fisher Scientific PARN Monoclonal Antibody (UMAB143), UltraMAB
Human PARN 단백질을 인식하는 UMAB143 클론의 Mouse Monoclonal Antibody. Western blot, IHC(P), ChIP 등 다양한 응용 가능. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:200
ChIP Assay (ChIP)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB143 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human PARN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a 3′-exoribonuclease, similar to the RNase D family of 3′-exonucleases. It preferentially degrades poly(A) tails of mRNAs, initiating eukaryotic mRNA decay. This protein also participates in silencing maternal mRNAs during oocyte maturation and early embryonic development, and in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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