Thermo Fisher Scientific Astrin/MAP126 Polyclonal Antibody
Astrin/MAP126 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IP 실험에 적합합니다. 인간 SPAG5 단백질의 875-925번째 잔기 영역을 면역원으로 사용하였으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A301512Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Astrin/MAP126 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 875 and 925 of human astrin (mitotic spindle associated protein p126) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon, and thymus.
It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase, being essential for proper spindle formation and dynamic regulation of mitotic spindles.
SPAG5 also plays roles in sister chromatid cohesion and separation, contributing to chromosome integrity. It forms homodimers with a long stalk and globular head domain. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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