
Thermo Fisher Scientific cGKII Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 cGKII 단백질 특이적 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human CGK2 (aa 92–141) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2635275 |
Product Specific Information
The antibody detects endogenous levels of total cGKII protein.
Target Information
PRKG2 (PKG2, cGKII) exhibits many cellular functions and has cAMP- and cGMP-dependent protein kinase activity. cGKII is thought to play a key role in diverse physiological pathways. It may mediate intestinal secretion of water and electrolytes induced by the E. coli toxin STa and the intestinal peptide guanylin. cGKII is also postulated to act as a molecular switch that couples the cessation of proliferation and the start of hypertrophic chondrocyte differentiation through attenuating SOX9 function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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