Thermo Fisher Scientific Fumarase Polyclonal Antibody
Thermo Fisher Scientific의 Fumarase Polyclonal Antibody는 인간 Fumarase 단백질을 인식하는 토끼 다클론 항체입니다. WB, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며, 안정적인 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Fumarase (amino acid range 45–188 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903628 |
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (Krebs) cycle and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and mitochondrial forms, differing by the translation start site. The mitochondrial form is generated by removal of the N-terminal extension. This enzyme functions as a homotetramer and is similar to thermostable class II fumarases. Mutations in this gene can cause fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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