Thermo Fisher Scientific Fumarase Polyclonal Antibody
Thermo Fisher Scientific의 Fumarase Polyclonal Antibody는 마우스 반응성을 가진 토끼 IgG 항체로, Western blot, IHC, ICC/IF 등에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% 글리세롤 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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- PA5119129
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Fumarase (amino acid range 42–185 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903629 |
Target Information
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle (Krebs cycle) and catalyzes the formation of L-malate from fumarate. It exists in both cytosolic and N-terminal extended mitochondrial forms, differing in translation start sites. The mitochondrial form loses its extension to match the cytoplasmic version. It functions as a homotetramer and shares similarity with thermostable class II fumarases. Mutations in this gene can result in fumarase deficiency, leading to progressive encephalopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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