Thermo Fisher Scientific RPE65 Polyclonal Antibody
RPE65 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot 및 Immunocytochemistry에 적합하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 시각 주기 관련 연구에 유용합니다.
- 카탈로그번호
- PA5115852
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RPE65 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPE65 (Accession Q16518), corresponding to amino acid residues A28–T78 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900486 |
Product Specific Information
This antibody detects endogenous levels of total RPE65.
Target Information
RPE65 is a major protein of the retinal pigment epithelium (RPE). It is essential for the regeneration of rhodopsin in the visual cycle. Mutations in RPE65 cause certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA). Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and leads to the accumulation of retinyl esters in the RPE.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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