Thermo Fisher Scientific NFS1 Monoclonal Antibody (OTI2H5), TrueMAB
NFS1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합합니다. Human 시료에 반응하며, 고순도의 affinity chromatography로 정제되었습니다. PBS/BSA/glycerol buffer에 보관되며 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–299 of human NFS1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family.
It localizes to the cytoplasm or mitochondrion depending on cytosolic pH. NFS1 shows highest expression in heart and skeletal muscle, with lower expression in liver, brain, and pancreas.
NFS1 catalyzes the removal of sulfur from cysteine to form alanine, supplying inorganic sulfur for iron-sulfur (Fe-S) clusters. These clusters are essential cofactors in processes such as electron transfer in oxidative phosphorylation, enzymatic catalysis in aconitase and dehydratases, and maintaining structural integrity in DNA repair enzymes like endonuclease III.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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