Thermo Fisher Scientific GTF2IRD1 Polyclonal Antibody
Thermo Fisher Scientific의 GTF2IRD1 Polyclonal Antibody는 인간 GTF2IRD1 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot, IHC, ICC/IF에 적합하며 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GTF2IRD1. Recombinant protein control fragment (Product #RP-102459). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790870 |
Product Specific Information
Immunogen sequence:
RPCTYGVPKL KRILEERHSI HFIIKRMFDE RIFTGNKFTK DTTKLEPASP PEDTSAEVSR ATVLDLAGNA RSDKGSMSED CGPGTSGELG GLRPIKIEPE DLDIIQVTVP DPSPTSEEMT DSMPGHLPSE DSGYGMEMLT D
Target Information
Williams-Beuren syndrome (WBS) is a developmental disorder caused by a hemizygous microdeletion on chromosome 7q11.23. WBS is an autosomal dominant genetic condition characterized by physical, cognitive, and behavioral traits.
Physical traits include facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies, and neurologic and musculoskeletal abnormalities.
Cognitive and behavioral traits include mild retardation, weakness in visual-spatial skills, anxiety, and short attention span.
The WBSCR11 gene, also known as GRF2IRD1, GTF3, Cream1, and MusTRD1 in human and BEN in mouse, is located within the WBS deletion region. It is expressed in all adult tissues with several variants and shows discrete spatial and temporal expression during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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