Thermo Fisher Scientific Ribonucleotide Reductase M1/RRM1 Recombinant Rabbit Monoclonal Antibody (RRM1, 4372R)
RRM1 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체로, IHC 및 Peptide Array에 적합합니다. HEK293 발현 시스템에서 생산되며, 고순도 Protein A/G 정제 및 PBS 저장 버퍼를 사용합니다. 연구용으로 DNA 합성 관련 RRM1 검출에 활용됩니다.
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Thermo Fisher Scientific Ribonucleotide Reductase M1/RRM1 Recombinant Rabbit Monoclonal Antibody (RRM1, 4372R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RRM1, 4372R |
| Immunogen | Synthetic peptide corresponding to residues within aa700–800 of human RRM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis.
RRM1 is involved in carcinogenesis and tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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