Thermo Fisher Scientific RPL29 Polyclonal Antibody
Thermo Fisher Scientific의 RPL29 Polyclonal Antibody는 인간 RPL29 단백질에 특이적인 토끼 IgG 항체로, WB, IHC, ICC/IF에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RPL29. Recombinant protein control fragment (Product #RP-104235) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646740 |
Product Specific Information
Immunogen sequence: PASVPAQAPK RTQAPTKASE
Highest antigen sequence identity to the following orthologs: Mouse – 65%, Rat – 65%.
Target Information
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.
Different members of this family show distinct substrate specificities for MAPKs, tissue distribution, subcellular localization, and inducibility by extracellular stimuli.
This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. It is evenly distributed in both cytoplasm and nucleus and is widely expressed in various tissues and organs, with elevated expression under stress stimuli.
Three transcript variants encoding two different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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