Thermo Fisher Scientific MMP27 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MMP27. Recombinant protein control fragment (Product #RP-104100). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MMP27,uniProtId:Q9H306-1,ncbiNodeId:9606,antigenRange:321-386,antigenLength:513,antigenImageFileName:PA5-64398_MMP27_Q9H306-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64398_MMP27_Q9H306-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644015

Product Specific Information

Immunogen sequence: FWPSLPADLQ AAYENPRDKI LVFKDENFWM IRGYAVLPDY PKSIHTLGFP GRVKKIDAAV CDKTTR

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 83%.

Target Information

Metalloproteinases (MMPs) are a family of proteins that are involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling and embryonic development. MMPs are crucial in tumor invasion and building of metastatic formations because of their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins and/or collagen. MMP-27 (matrix metallopeptidase 27) is a 513 amino acid secreted protein that is expressed in B-cells. Belonging to the peptidase M10A family, MMP-27 contains four hemopexin-like domains, which is suggested to be involved in substrate recognition. MMP-27, along with other MMP family members, is associated with breast cancer development and tumor progression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.