Thermo Fisher Scientific MMP27 Polyclonal Antibody
Human MMP27 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:1,000~1:2,500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. MMP27 관련 종양 연구 및 세포 외기질 분해 연구에 적합.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MMP27. Recombinant protein control fragment (Product # RP-104100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644015 |
Product Specific Information
Immunogen sequence:
FWPSLPADLQ AAYENPRDKI LVFKDENFWM IRGYAVLPDY PKSIHTLGFP GRVKKIDAAV CDKTTR
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 83%
Target Information
Metalloproteinases (MMPs) are a family of proteins involved in the breakdown of the extracellular matrix during normal cellular events, including reproduction, tissue remodeling, and embryonic development.
MMPs are crucial in tumor invasion and metastasis formation due to their ability to degrade extracellular matrix proteins such as fibronectin, laminin, gelatins, and collagens.
MMP-27 (Matrix Metallopeptidase 27) is a 513 amino acid secreted protein expressed in B-cells.
It belongs to the peptidase M10A family and contains four hemopexin-like domains, which are suggested to be involved in substrate recognition.
MMP-27 and other MMP family members are associated with breast cancer development and tumor progression.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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