Thermo Fisher Scientific SPTBN1 Polyclonal Antibody
Rabbit Polyclonal Antibody로, SPTBN1 단백질을 인식합니다. Western Blot, IHC, IP 등 다양한 응용에 적합하며, 4°C에서 보관합니다. 비결합형 액상 형태로 공급되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2150 and 2200 of Human Spectrin Non-Erythroid Beta 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps cells maintain their characteristic biconcave shape while remaining flexible and elastic.
Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit, which associate in an antiparallel configuration to form a 100 nm rod-like structure.
Spectrin in other tissues may consist of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin.
A newly introduced nomenclature designates the erythrocyte subunits as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e.g., beta-1 epsilon-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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