Thermo Fisher Scientific RFTN1 Polyclonal Antibody
RFTN1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 ELISA에 적합. Human, Mouse, Rat 시료에 반응하며, 세포막 단백질 Raftlin 연구에 활용 가능. PBS/glycerol buffer로 안정화되어 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–260 of human RFTN1 (NP_055965.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.83 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804485 |
Product Specific Information
Immunogen sequence:
MGCGLNKLEK RDEKRPGNIY STLKRPQVET KIDVSYEYRF LEFTTLSAAE LPGSSAVRLA SLRDLPAQLL ELYQQGFSLA ALHPFVQPTH EREKTPLEHI FRAILIKKTD RSQKTDLHNE GYILELDCCS SLDHPTDQKL IPEFIKKIQE AASQGLKFVG VIPQYHSSVN SAGSSAPVST ANSTEDARDA KNARGDHASL ENEKPGTGDV CSAPAGRNQS PEPSSGPRGE VPLAKQPSSP SGEGDGGELS PQGVSKTLDG
Positive Samples: A-549, Mouse liver
Cellular Location: Cell membrane, Lipid-anchor
Target Information
Raftlin (RFTN1, raftlin lipid raft linker 1) is a 578 amino acid cell membrane lipid-anchored protein essential for raft cell assembly and maintenance. It modulates B-cell antigen receptor-mediated signaling, TCR signals, and participates in T cell-mediated immune responses.
The RFTN1 gene is located on human chromosome 3, which contains over 1,100 genes including chemokine receptor clusters and tumor suppressor loci such as RASSF1, HYAL1, and SEMA3B.
Mutations in genes on chromosome 3 are associated with genetic diseases such as Marfan Syndrome, Porphyria, von Hippel-Lindau Syndrome, Osteogenesis Imperfecta, and Charcot-Marie-Tooth Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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