Thermo Fisher Scientific LMAN1 Polyclonal Antibody
LMAN1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 고순도 Affinity Chromatography 정제, 안정적인 PBS/glycerol buffer 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific LMAN1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 270–480 of human LMAN1 (NP_0055611) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.02 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804490 |
Product Specific Information
- Immunogen sequence:
PGKEPPTPDK EISEKEKEKY QEEFEHFQQE LDKKKEEFQK GHPDLQGQPA EEIFESVGDR ELRQVFEGQN RIHLEIKQLN RQLDMILDEQ RRYVSSLTEE ISKRGAGMPG QHGQITQQEL DTVVKTQHEI LRQVNEMKNS MSETVRLVSG MQHPGSAGGV YETTQHFIDI KEHLHIVKRD IDNLVQRNMP SNEKPKCPEL PPFPSCLSTV H - Positive Samples: BT-474, LO2, U-251MG
- Cellular Location: Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Golgi apparatus membrane, Single-pass membrane protein, Single-pass type I membrane protein
Target Information
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, recycling between the two compartments. It is a mannose-specific lectin and a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in this gene are associated with a coagulation defect, identified as the disease gene leading to combined factor V–factor VIII deficiency, a rare autosomal recessive disorder with diminished coagulation factors V and VIII.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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