Thermo Fisher Scientific SIN3A Polyclonal Antibody
Human Sin3A 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC 및 ICC/IF에 사용 가능하며, 고순도 Protein A 및 항원 친화 크로마토그래피로 정제됨. 액상 형태로 1 mg/mL 농도, PBS buffer 내 ProClin 300 포함, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of Human Sin3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2788276 |
Product Specific Information
This antibody has specificity for Human Sin3A.
Target Information
Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B. Containing four paired amphipathic helix domains (PAH domains), mSin3A and mSin3B directly interact with several transcriptional repressor proteins, including HDAC1, HDAC2, RbAp46, MeCP2, Mad/Max heterodimer, SMRT, and N-CoR.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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