Thermo Fisher Scientific MAGE1 Monoclonal Antibody (MA454)
MAGE1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 IHC(P)에서 사용 가능. 인간 및 랫트 반응성. 암 면역치료 연구 및 종양 표지 분석에 적합. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific MAGE1 Monoclonal Antibody (MA454)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MA454 |
| Immunogen | Recombinant protein MAGE1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Breast cancer tissues
- Cellular location: Cytoplasmic
Target Information
Human malignant neoplasms carry rejection antigens recognized by autologous, tumor-directed, CD8+ cytolytic T lymphocyte clones (CTLs).
An important group of these antigens is encoded by the MAGE family of genes. MAGE-1 is expressed in a significant proportion of human neoplasms (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) but not in normal tissues.
Therefore, the encoded antigen may serve as a marker for early detection and as a potential target for cancer immunotherapy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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