Thermo Fisher Scientific hnRNP D Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 사용 가능한 Rabbit Polyclonal 항체. Human hnRNP D 단백질 인식. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HNRNPD. Recombinant protein control fragment (Product #RP-102523). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789343 |
Product Specific Information
Immunogen sequence:
RGFCFITFKE EEPVKKIMEK KYHNVGLSKC EIKVAMSKEQ YQQQQQWGSR GGFAGRARGR GGDQQSGYGK VS
Target Information
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and influence pre-mRNA processing and mRNA metabolism and transport. While most hnRNPs are nuclear, some shuttle between the nucleus and cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The encoded protein contains two quasi-RRM domains that bind RNAs and localizes to both nucleus and cytoplasm. It is implicated in regulation of mRNA stability. Alternative splicing results in four transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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