Thermo Fisher Scientific DYRK2 Monoclonal Antibody (599542)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

8-25 µg/mL

-

Immunohistochemistry (Frozen) (IHC (F))

8-25 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

599542

Immunogen

E. coli-derived recombinant human DYRK2 (aa 1-107) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DYRK2,uniProtId:Q92630-1,ncbiNodeId:9606,antigenRange:1-107,antigenLength:601,antigenImageFileName:MA5-24269_DYRK2_Q92630-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24269_DYRK2_Q92630-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606267

Product Specific Information

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

DYRK2 (also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2) belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. DYRK2 also regulates p53 to induce apoptosis in response to DNA damage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.