Thermo Fisher Scientific Human APRIL Synthetic Peptide
Human APRIL 단백질의 13개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 차단용 블로킹 펩타이드로 사용 가능하며, 면역반응 및 세포사멸 연구에 적합합니다. PBS 버퍼에 0.1% BSA와 0.02% sodium azide를 포함하며, -20°C에서 보관합니다.
- 카탈로그번호
- PEP0067
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the extracellular domain of human APRIL.
PEP-0067 can be used as a blocking peptide with polyclonal antibody PA5-19942.
Target Information
Members in the TNF superfamily regulate immune responses and induce apoptosis.
A novel member in the TNF family was recently identified by several groups and designated APRIL (A PRoliferation-Inducing Ligand), TALL2 (TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (TNF related death ligand 1a) in human and mouse.
Two receptors for APRIL were recently identified and designated TACI and BCMA.
APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death.
APRIL and its close relative BlyS, along with their receptors BCMA and TACI, are involved in diseases of autoimmunity and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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