Thermo Fisher Scientific FGFBP1 Polyclonal Antibody
Human FGFBP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 완충액에 보존. 세포 증식 및 암 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FGFBP1. Recombinant protein control fragment (Product #RP-101020) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641611 |
Product Specific Information
Immunogen sequence:
DHEFSCVFAG NPTSCLKLKD ERVYWKQVAR NLRSQKDICR YSKTAVKTRV CRKDFPESSL KLVSSTLFGN TKPRKEKTEM SPREHIKGKE TTPSSLAVTQ TMATKAPECV EDPDMANQRK TALEFCGETW SSLCTFFL
Sequence identity:
Highest antigen sequence identity to the following orthologs:
- Mouse: 64%
- Rat: 59%
Target Information
FGFBP1 encodes a secreted fibroblast growth factor carrier protein.
This protein plays a critical role in:
- Cell proliferation, differentiation, and migration
- Binding to fibroblast growth factors and enhancing their biological effects
- Acting as an angiogenic switch molecule in tumor growth
- Being associated with cancers such as pancreatic and colorectal adenocarcinoma
A pseudogene of FGFBP1 is located on the short arm of chromosome 4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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