Thermo Fisher Scientific CRP Polyclonal Antibody
CRP 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. ELISA, IP, RIA 등 다양한 면역학적 분석에 적용 가능하며, 고순도 및 안정적 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CRP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry (Flow) | - | View 1 publication |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Radioimmune Assays (RIA) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Bovine |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Purified human C-reactive protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 9.9 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | PBS, pH 7.2–7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2085518 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CRP (C-reactive protein) is a major cyclic, pentameric acute phase protein composed of five identical, noncovalently bound, nonglycosylated subunits. Each subunit consists of 206 amino acids with a molecular weight of 24 kDa.
CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes. It initiates the classical complement cascade, binds to nuclear components (chromatin, histones, etc.), and plays an important role in innate immunity.
CRP acts as an opsonin and activator of monocytes/macrophages, binding to nuclear components such as chromatin, histones, and snRNP, suggesting a scavenger role during cell necrosis.
It contributes to host defense by recognizing foreign pathogens and damaged host cells, initiating their elimination via humoral and cellular effector systems. Elevated basal CRP levels are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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