Thermo Fisher Scientific Phospho-RSK2 (Ser369) Polyclonal Antibody
RSK2 단백질의 Ser369 위치에서 인산화된 형태를 특이적으로 검출하는 polyclonal antibody. Western blot, IHC, ICC/IF에 적합하며 인간과 생쥐 시료 반응. 고순도 정제 및 안정적 PBS/glycerol 저장 포뮬러로 연구용에 최적화됨.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RPS6KA3 (Accession P51812), corresponding to amino acid residues around phosphorylated Ser369 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817014 |
Product Specific Information
This antibody detects endogenous levels of RSK2 only when phosphorylated at Ser369.
Target Information
RPS6KA3 (RSK2) is a serine/threonine kinase that regulates multiple cellular processes including transcription, adhesion, growth, survival, and proliferation. It contains two distinct kinase domains and phosphorylates various substrates, including members of the MAPK signaling pathway. The activity of RSK2 is associated with cell growth and differentiation, and mutations in the RPS6KA3 gene are linked to Coffin-Lowry syndrome (CLS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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