Thermo Fisher Scientific Versican Monoclonal Antibody (N351/23), APC

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:100

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

N351/23

Immunogen

Fusion protein amino acids 362-585 (glycosaminoglycan alpha domain) of mouse Versican core protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Versican,uniProtId:Q62059-1,ncbiNodeId:10090,antigenRange:362-585,antigenLength:3357,antigenImageFileName:MA5-45623_Versican_Q62059-1_House_mouse.svg,antigenImageFileNamePDP:MA5-45623_Versican_Q62059-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

APC APC APC

View additional formats

• Unconjugated
• FITC
• PE
• PerCP
• Request custom conjugation

Excitation/Emission Max

651/660 nm View spectra

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

95.64mM phosphate/2.48mM MES, pH 7.4, with 2M EDTA

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2932077

Product Specific Information

1 µg/mL of MA5-45623 was sufficient for detection of Versican in 20 µg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.|Detects >350kDa.

This antibody was formerly sold as clone S351-23.

Target Information

Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican`s existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.