Thermo Fisher Scientific FTO Polyclonal Antibody
FTO 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인체 반응성을 가지며, 다양한 종에서 예측 반응성을 보입니다. 0.5 mg/mL 농도의 액상 형태로 TBS 버퍼에 보관됩니다.
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Thermo Fisher Scientific FTO Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.03–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QQKPDCRPYWEKDD) corresponding to internal amino acids of FTO (aa 476–481) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979809 |
Product Specific Information
- Predicted to react with canine, mouse, porcine, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)- and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicate that both 2-oxoglutarate and iron are important for FTO function. Though not much is yet known about FTO, it is thought that the protein may modify the activity of genes involved in metabolism and fat storage, potentially influencing obesity risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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