
Thermo Fisher Scientific CD268/BAFFR/TNFRSF13C Monoclonal Antibody (BAFFR, 1558)
인간 CD268/BAFFR/TNFRSF13C를 인식하는 Mouse IgG1 단일클론 항체. IHC 및 Flow Cytometry에 적합하며, Protein A로 정제된 액상 형태. BAFFR 관련 B세포 생존 및 발달 연구에 활용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BAFFR, 1558 |
| Immunogen | Recombinant full-length human CD268 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), also known as BAFFR, is a protein encoded by the TNFRSF13C gene in humans.
The BAFFR gene is mapped to chromosome 22q13.1–q13.31.
It encodes a 184 amino acid transmembrane protein that shares 56% identity with the mouse protein.
B cell-activating factor (BAFF) enhances B-cell survival in vitro and regulates the peripheral B-cell population.
BAFF plays a crucial role in B cell development and can function through receptors other than BCMA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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