Thermo Fisher Scientific PCDH1 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A549, HeLa, HepG2, HCT116
• Predicted reactivity: Mouse (97%), Bovine (98%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. It belongs to the delta1-protocadherin family, which includes protocadherin-1, -7, -9, and -11(X/Y). These proteins have seven extracellular cadherin repeats, a transmembrane domain, and a cytoplasmic domain, and can exist in both short and long isoforms.

Expression of PCDH1 is temporally and spatially regulated and plays a role in early development and mature tissues. In mice, it is expressed in the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and seminal gland. PCDH1 has been identified as a susceptibility gene for bronchial hyperresponsiveness in humans and is expressed on human pluripotent stem cells.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.