Thermo Fisher Scientific PCDH1 Polyclonal Antibody
PCDH1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 분석에 적합합니다. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 간 접착 관련 연구 및 PCDH1 발현 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 710–971 of PCDH1 (Uniprot ID: Q08174) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154296 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (97%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Protocadherin 1 (PCDH1), also known as cadherin-like protein 1, is a transmembrane protein involved in cell-cell adhesion. It belongs to the delta1-protocadherin family, which includes protocadherin-1, -7, -9, and -11(X/Y). These proteins have seven extracellular cadherin repeats, a transmembrane domain, and a cytoplasmic domain, and can exist in both short and long isoforms.
Expression of PCDH1 is temporally and spatially regulated and plays a role in early development and mature tissues. In mice, it is expressed in the brain, spinal cord, peripheral ganglia, inner ear, hair follicles, kidney, reproductive organs, prostate, and seminal gland. PCDH1 has been identified as a susceptibility gene for bronchial hyperresponsiveness in humans and is expressed on human pluripotent stem cells.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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