Thermo Fisher Scientific Pan RhO Polyclonal Antibody
Rho 단백질 패밀리를 인식하는 sheep polyclonal antibody로, Western blot 및 IHC에 적합합니다. Human, Mouse, Rat 시료에서 반응하며 PBS buffer에 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- OSC00095G-500UG
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | - |
| Immunohistochemistry (IHC) | 10–50 µg/mL | - |
| Miscellaneous (PubMed) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 50–100 of RhOA, RhOB, RhOC, RhOF, RhOQ and RAC1, RAC2, RAC3, and CDC42 conjugated to blue carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: RhO family.
Target Information
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.
Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is prenylated at its C-terminus and localizes to the cytoplasm and plasma membrane. It plays a key role in cell locomotion, and overexpression is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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