Thermo Fisher Scientific Actin Muscle Monoclonal Antibody (MSA06 (HUC1-1))
Actin Muscle Monoclonal Antibody (MSA06, HUC1-1)은 alpha-smooth, skeletal, cardiac muscle actin을 인식하는 pan muscle 항체입니다. Western blot과 IHC에 적합하며, 다양한 근육 및 종양 연구에 활용됩니다. 4°C 보관, 액상 형태, 연구용 전용 시약입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Published species | Fish, Mouse, Zebrafish |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MSA06 (HUC1-1) |
| Immunogen | Purified actin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
| RRID | AB_10989678 |
Product Specific Information
This antibody reacts with alpha-smooth muscle, alpha-skeletal, and alpha-cardiac (sarcomeric) actins. It serves as a pan muscle actin antibody and reacts with tumors arising from smooth muscle (leiomyosarcomas) as well as skeletal muscle tumors (rhabdomyosarcomas).
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved and play critical roles in cell motility, structure, and integrity.
Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actins: Major constituents of the contractile apparatus
- Beta and gamma actins: Involved in regulation of cell motility
This actin is an alpha actin found in skeletal muscle. Mutations in this gene cause several congenital myopathies, including nemaline myopathy type 3, congenital myopathy with excess thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion—conditions that lead to muscle fiber defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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