Thermo Fisher Scientific Human DYRK1A Synthetic Peptide
Human DYRK1A 단백질의 C-말단 17개 아미노산 서열로 구성된 합성 펩타이드. DYRK1A 항체(PA5-21124)와 함께 블로킹 실험에 사용 가능. 액상 형태, 200 µg/mL 농도, PBS(pH 7.2) 내 0.1% BSA 및 0.02% sodium azide 포함. -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human DYRK1A.
PEP-1238 can be used as a blocking peptide with polyclonal antibody PA5-21124.
Target Information
DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21 and has been implicated in the pathogenesis of this disease. DYRK1A catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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