Thermo Fisher Scientific COX6c/Cytochrome C Oxidase subunit VIc Polyclonal Antibody
COX6c/Cytochrome C Oxidase subunit VIc 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human COX6c/Cytochrome C Oxidase subunit VIc (amino acids 21–75) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially encoded subunits function in electron transfer, while the nuclear-encoded subunits may be involved in regulation and assembly of the complex.
This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc and is up-regulated in prostate cancer cells. A pseudogene has been identified on chromosome 16p12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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