Thermo Fisher Scientific CYP1B1 Polyclonal Antibody
CYP1B1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Protein A 정제 및 TBS 기반 완충액에 보관됩니다. 약물 대사 및 안구 발달 관련 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human CYP1B1 (amino acids 441–543) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CYP1B1 is a 543-amino-acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 superfamily of enzymes, which are monooxygenases catalyzing reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids. This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17β-estradiol. It also participates in the metabolism of substances active in eye growth and differentiation, playing a potential role in ocular development. Mutations in CYP1B1 are associated with primary congenital glaucoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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