Thermo Fisher Scientific CLEC12A Polyclonal Antibody
CLEC12A 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 적합하며 인간 CLEC12A의 모든 알려진 isoform을 인식. 액상 형태로 제공되며 0.5 mg/mL 농도, -20°C에서 보관 권장.
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Applications
Tested Application
- Western Blot (WB): 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-NPVQLGSTYFRE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933822 |
Product Specific Information
- This antibody is expected to recognize all reported isoforms (NP_612210.4; NP_963917.2; NP_001193939.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
CD371, also known as CLEC12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL), is a highly glycosylated transmembrane receptor containing a cytoplasmic ITIM domain that associates with SHP1 and SHP2.
It is mainly expressed on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression on NK cells remains controversial.
Although its function is not fully understood, studies suggest involvement in inflammation and LPS activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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