Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI4C6), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution

• 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

The CD4 antigen is involved in recognition of MHC class II molecules and acts as a co-receptor for HIV.
CD4 is mainly expressed on T helper cells but can also be found on monocytes, macrophages, and dendritic cells.
Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 assists in T-cell activation via interaction with the T-cell receptor complex and tyrosine kinase Lck, and may mediate neuronal damage in immune-related CNS diseases.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.