Thermo Fisher Scientific PAX5 Monoclonal Antibody (OTI5A6), TrueMAB
PAX5 단백질을 인식하는 Mouse Monoclonal Antibody로, WB 및 IHC(P) 응용에 적합. 고순도 친화 크로마토그래피 정제. Lyophilized 형태로 제공되며, 재구성 시 1 mg/mL 농도. B세포 분화 및 신경 발달 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5A6 |
| Immunogen | Full length human recombinant protein of human PAX5 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PAX5 is a member of the paired box (PAX) family of transcription factors. PAX proteins regulate early development, and altered expression may contribute to neoplastic transformation.
PAX5 functions as a B-cell lineage-specific activator protein (BSAP), expressed at early but not late stages of B-cell differentiation. It is also found in developing CNS and testis, suggesting roles in neural development and spermatogenesis.
Mutations in the PAX5 gene can result in leukemia, including acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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