Thermo Fisher Scientific PAX5 Monoclonal Antibody (OTI5A6), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

PAX5 is a member of the paired box (PAX) family of transcription factors. PAX proteins regulate early development, and altered expression may contribute to neoplastic transformation.
PAX5 functions as a B-cell lineage-specific activator protein (BSAP), expressed at early but not late stages of B-cell differentiation. It is also found in developing CNS and testis, suggesting roles in neural development and spermatogenesis.
Mutations in the PAX5 gene can result in leukemia, including acute lymphoblastic leukemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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