Thermo Fisher Scientific CD298 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total ATP1B3.

Target Information

The protein encoded by this gene belongs to the family of Na⁺/K⁺ and H⁺/K⁺ ATPases beta chain proteins, and to the subfamily of Na⁺/K⁺-ATPases. Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of various organic and inorganic molecules, and for the electrical excitability of nerve and muscle cells.
This enzyme is composed of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na⁺/K⁺-ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit, and a pseudogene for this gene exists on chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.