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Thermo Fisher Scientific Phospho-EIF4B (Ser422) Polyclonal Antibody
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Phospho-EIF4B (Ser422) 항체로 인산화된 eIF4B 단백질을 특이적으로 검출합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. Rabbit polyclonal IgG로 높은 특이성과 재현성을 제공합니다. 연구용으로 단백질 인산화 신호 분석에 활용됩니다.
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마지막 업데이트 2025. 08. 05. 오후 02:18
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Thermo Fisher Scientific PA599472 Phospho-EIF4B (Ser422) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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627,600원VAT 포함 690,360원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-EIF4B (Ser422) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EIF4B (Accession P23588), corresponding to amino acid residues around phosphorylated Ser422 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818405 |
Product Specific Information
This antibody detects endogenous levels of eIF4B only when phosphorylated at Ser422.
Target Information
The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A, binding near the 5′-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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