Thermo Fisher Scientific EAR2 Polyclonal Antibody
EAR2(NR2F6) 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에서 WB, IHC, ChIP에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공. 단백질 발현 및 전사 조절 연구에 적합.
- 카탈로그번호
- PA527135
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | - |
| ChIP assay (ChIP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 344–404 of NR2F6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2544611 |
Product Specific Information
- Recommended positive controls: HeLa, Raji, NIH-3T3, JC
- Predicted reactivity: Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements containing imperfect 5'-AGGTCA-3' repeats recognized by other nuclear hormone receptors. Modulates hormonal responses and represses transcriptional activity of several genes including LHCGR, REN, and OXT. Represses thyroid hormone receptor gene activity in a cell type-specific manner, inhibits NFATC transcription factor DNA binding, and represses IL-17 expression in Th-17 CD4(+) T cells. Plays a role in forebrain circadian clock development and is required early in the development of the locus coeruleus (LC).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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