Thermo Fisher Scientific TAP1 Polyclonal Antibody
TAP1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. Human 및 Rat 시료에 반응하며, HeLa lysate를 양성 대조로 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1:4,000 | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Immunoprecipitation (IP) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide AKLVQRQMLGLQPA, corresponding to amino acids 735–748 of Human TAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2200193 |
Product Specific Information
Recommended positive control: HeLa cell lysate.
Target Information
The membrane-associated protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intracellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein is part of the MDR/TAP subfamily, which is involved in multidrug resistance. TAP1 is responsible for pumping degraded cytosolic peptides across the endoplasmic reticulum membrane into the compartment where class I molecules assemble.
Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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