Thermo Fisher Scientific Phospho-Parkin (Ser378) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phospho-Parkin (Ser378). Western blot validated. Suitable for studying Parkin phosphorylation and Parkinson’s disease mechanisms. Frozen form, stored at -20°C for long-term stability.
- 카탈로그번호
- 480027
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the phospho-Ser378 of human parkin |
| Conjugate | Unconjugated |
| Form | Frozen |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C |
| Shipping Conditions | Wet ice |
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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