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Thermo Fisher Scientific Phospho-PAK1/2/3 (Thr402) Polyclonal Antibody
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PAK1/2/3 단백질의 인산화 형태(Thr402)를 특이적으로 인식하는 폴리클로날 항체입니다. Western blot에 최적화되어 있으며, 세포 신호전달 및 단백질 활성 연구에 유용합니다. Rabbit IgG 기반으로 액상 형태이며, 냉장 또는 냉동 보관 가능합니다.
- 카탈로그번호
- 480025
- 판매단위
- pk
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마지막 업데이트 2025. 08. 03. 오후 03:47
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Thermo Fisher Scientific 480025 Phospho-PAK1/2/3 (Thr402) Polyclonal Antibody 100 ul pk판매 단위 pk
재고 1개
539,400원VAT 포함 593,340원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-PAK1/2/3 (Thr402) Polyclonal Antibody
Thermo Fisher Scientific Phospho-PAK1/2/3 (Thr402) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr402 of rat p21 activated kinase 2 (PAK-2). The peptide sequence used is identical in PAK-1, 2 and 3. Note: Thr402 in PAK-2 corresponds to Thr423 in human PAK-1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532247 |
Target Information
In mammals, several isoforms of p21-Activated Protein Kinases (PAKs) have been identified:
- alpha-PAK (PAK-1) and beta-PAK (PAK-3) are mostly brain-specific.
- gamma-PAK (PAK-2) is expressed ubiquitously (Jakobi et al., 2003).
Mutations in the PAK-3 gene are associated with X-linked mental retardation. PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004).
PAK-3 also plays a role in regulating cell shape, motility, and cell death (Jakobi et al., 2003; Walter et al., 1998).
Autophosphorylation of Thr402 is essential for activation of PAK (Jakobi et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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