Thermo Fisher Scientific Phospho-DOK2 (Tyr345) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human DOK2(Accession O60496), corresponding to amino acid residues around phosphorylated Tyr345. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DOK2,uniProtId:O60496-1,ncbiNodeId:9606,antigenRange:345,antigenLength:412,antigenImageFileName:PA5-105126_DOK2_O60496-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105126_DOK2_O60496-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816599

Product Specific Information

Antibody detects endogenous levels of DOK2 only when phosphorylated at Tyr345, which site historically referenced as Tyr351.

Target Information

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.