Thermo Fisher Scientific PAK4 Monoclonal Antibody (OTI3C3), TrueMAB
PAK4 단백질을 인식하는 Mouse Monoclonal 항체로 Western blot에 적합합니다. Human 시료에 반응하며, 동결건조 형태로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 세포골격 재조직과 암 관련 연구에 유용합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PAK4 Monoclonal Antibody (OTI3C3), TrueMAB
Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–308 of human PAK4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PAK4 is a serine/threonine p21-activating kinase involved in actin cytoskeleton reorganization and filopodia formation.
PAK family proteins are divided into two groups:
- Group I: PAK1, PAK2, PAK3 (activated by Cdc42/Rac binding)
- Group II: PAK4, PAK5, PAK6 (not activated by Cdc42/Rac binding)
PAK4 acts as a novel effector of Cdc42Hs, inducing filopodia formation and actin polymerization, and is essential for embryonic viability and neuronal development. It also plays a role in anchorage-independent tumor cell growth and activation of cancer prosurvival pathways.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.