Thermo Fisher Scientific Human CCL20 (MIP-3 alpha) Recombinant Protein

Applications

• Western Blot (WB): Assay-dependent
• Immunohistochemistry (IHC): Assay-dependent
• ELISA: Assay-dependent
• Functional Assay: Assay-dependent
• Control (Ctrl): Assay-dependent

Product Specifications

Product Specific Information

Carrier-Free

• Reconstitution: Briefly centrifuge vial before opening. Reconstitute recombinant human MIP-3α in sterile distilled water to 0.1–1.0 mg/mL. Make further dilutions in tissue culture-grade buffered solutions with heat-inactivated fetal calf serum or low endotoxin BSA.
• Storage: Lyophilized preparation is stable at 2–8°C; for long-term storage keep at -20°C, preferably desiccated. Store reconstituted aliquots at -20°C and avoid repeated freeze/thaw cycles.

Target Information

Macrophage Inflammatory Protein-3 alpha (MIP-3α), also known as CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. MIP-3α is strongly upregulated by inflammatory signals and downregulated by the anti-inflammatory cytokine IL-10. It signals through the G protein-coupled receptor CCR6 and acts as a chemoattractant for lymphocytes and dendritic cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.