Thermo Fisher Scientific c Myc tag Polyclonal Antibody
Rabbit polyclonal antibody recognizing c-Myc tag sequence EQKLISEEDL. Suitable for WB and IHC applications. Lyophilized form for long-term stability. For research use only, not for diagnostic or resale purposes.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Tag |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide EQKLISEEDL (410–419) from human c-Myc (c Myc tag) conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: c-Myc.
Target Information
Myc is a proto-oncogene encoding a nuclear phosphoprotein that regulates cell cycle progression, apoptosis, and cellular transformation. The protein forms a heterodimer with MAX, binding the E box DNA consensus sequence to regulate transcription of target genes.
Amplification of this gene is frequently observed in various human cancers. Translocations involving MYC are associated with Burkitt lymphoma and multiple myeloma.
Translation initiates from both an upstream non-AUG (CUG) and a downstream AUG start site, producing two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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