Thermo Fisher Scientific MBP Polyclonal Antibody
MBP 단백질을 표적하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 사용 가능. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적.
- 카탈로그번호
- OSM00069W-100UL
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MBP Polyclonal Antibody
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 100–140 of human MBP conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: MBP.
Target Information
The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. MBP-related transcripts are also expressed in bone marrow and the immune system. These mRNAs originate from the long MBP gene (Golli-MBP) containing three additional exons upstream of the classic MBP exons.
Alternative splicing produces two sets of MBP-related transcripts and proteins:
- Golli-MBP transcripts – contain unique Golli exons spliced to MBP exons, encoding hybrid proteins with N-terminal Golli and MBP sequences.
- Classic MBP transcripts – contain only MBP exons, producing well-characterized myelin basic proteins.
This conserved gene structure suggests an integral relationship between Golli and MBP transcription units, important for gene function and regulation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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