Thermo Fisher Scientific Contactin 2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Contactin 2 (CNTN2). Validated for Western blot with high purity (>95%). Suitable for human, mouse, and rat samples. Supplied as liquid, unconjugated form for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human Contactin 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803835 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system.
It is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains.
Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts to guide commissural axons without promoting their growth.
It binds with NgCAM in the plane of the same membrane (cis-binding). The heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains, while the homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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