Thermo Fisher Scientific Annexin A1 Polyclonal Antibody
Annexin A1 단백질에 특이적인 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. 전체 길이의 인간 Annexin I 단백질로 면역화됨. 항염증 연구 및 세포 신호전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | 24 |
| Immunohistochemistry (IHC) | – | 10 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:20–1:200 | 1 |
| Immunocytochemistry (ICC/IF) | 1 µg/mL | 9 |
| Flow Cytometry (Flow) | – | 4 |
| ELISA | 1:500–1:50,000 | 1 |
| Immunoprecipitation (IP) | – | 1 |
| Miscellaneous (PubMed) | – | 1 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length human recombinant Annexin I protein purified from yeast |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2533983 |
Product Specific Information
This antibody is specific for the Annexin I protein and does not cross-react with other Annexins. Reactivity with Annexin I was confirmed by Western blotting using total lysates derived from human fibroblasts.
Positive control lysates: human fibroblasts, mouse kidney, mouse lung, adult rat, and mouse brain.
Target Information
Annexin I belongs to a family of Ca²⁺-dependent phospholipid-binding proteins located on the cytosolic face of the plasma membrane. It has a molecular mass of approximately 40 kDa and exhibits phospholipase A₂ inhibitory activity. Since phospholipase A₂ is required for the biosynthesis of prostaglandins and leukotrienes, Annexin I may play a role in anti-inflammatory processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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