Thermo Fisher Scientific TFIP11 Polyclonal Antibody
TFIP11 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, Human에 반응하고 다른 종에도 예측 반응합니다. TBS 버퍼에 0.1% BSA, 0.09% sodium azide 포함, 4°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human tuftelin interacting protein 11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Dog, Rabbit, Pig, Orangutan, Monkey, and Chimpanzee.
Target Information
TFIP11 is involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover proceeds through two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15, it mediates the transition of the U2, U5, and U6 snRNP-containing IL complex to the snRNP-free IS complex, leading to efficient debranching and turnover of excised introns. It may also play a role in the differentiation of ameloblasts and odontoblasts or in the formation of the enamel extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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